Conclusions

T/O reduced the risk of CID compared with tio alone in the overall trial population, and in GOLD stage 2 and treatment-naïve patients

• Our results suggest that early treatment with T/O may be more effective than tio in preventing CID in these patient populations
• These results support clinically established data on patient outcomes, with greater improvements observed with T/O versus tio

Abbreviations: CID, clinically important deterioration; T/O, tiotropium/olodaterol; tio, tiotropium.